Determination of Anti-Cathepsin-D Antibodies in Human Blood Sera of Oncological Patients

Authors

  • I. Machová Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i, Prague | Department of Biochemistry and Microbiology, Institute of Chemical Technology, Prague
  • J. Zídková Department of Biochemistry and Microbiology, Institute of Chemical Technology, Prague
  • D. Springer Department of Clinical Biochemistry and Laboratory Medicine, First Faculty of Medicine, Charles University, Prague
  • V. Větvička Department of Pathology, University of Louisville, Louisville, USA
  • M. Fusek Department of Biochemistry and Microbiology, Institute of Chemical Technology, Prague

Keywords:

cancer, procathepsin D, autoantibodies against procathepsin D, ELISA

Abstract

In this study the levels of auto-antibodies formed against the activation peptide of procathepsin D were determined by the ELISA method using a synthetic multiantigen peptide containing the N-terminal amino acid sequence of the activation peptide of procathepsin D as a coating antigen. Based on the results auto-antibodies cannot be considered suitable cancer markers.

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Published

2012-08-15

How to Cite

Machová, I., Zídková, J., Springer, D., Větvička, V., & Fusek, M. (2012). Determination of Anti-Cathepsin-D Antibodies in Human Blood Sera of Oncological Patients. Chemické Listy, 106(8), 769–772. Retrieved from http://www-.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/874

Issue

Vol. 106 No. 8 (2012)

Section

Articles